Question: Where exactly does Scrubs take place? I mean, where is Sacred Heart? Is it ever mentioned in the show?
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Answer: Scrubs is filmed on location at North Hollywood Medical Center, a real decommissioned hospital located at 12629 Riverside Drive in the the North Hollywood neighborhood of Los Angeles, California; since 2007, the building is also the shooting location of semi-fictional medical series Diagnosis X. However, the location of Sacred Heart Hospital within the fictional world of Scrubs is left ambiguous. Cast and crew on the show refer to the location as "San DiFrangeles" - a portmanteau of San Diego, San Francisco, and Los Angeles that is meant to encompass a large part of California.
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