Directed by: Lloyd Kaufman, Michael Herz
Starring: Andree Maranda, Cindy Manion, Jennifer Babtist, Jennifer Prichard, Mitch Cohen
Audio problem: When Toxie is chasing Julie, Julie runs into a room, locks the door and puts a plank of wood to secure the door. As she does, she cries and whimpers, yet her mouth doesn't move.
Audio problem: When Toxie's fighting the nunchuck-wielding thug in the restaurant, he kicks them away once and they make noise when he does. When he does it again there's no sound at all. (00:36:00)
Continuity mistake: When Melvin falls into the toxic waste, he is wearing tights and a tutu, but when his stunt double runs up the street in flames, he's obviously wearing trousers and a shirt.
Officer O'Clancy: No way, you're wasting your time.
Cigar Face: That's where you're wrong. YOU'RE wasting our time. And now we're gonna waste you.
Trivia: A young Vincent D'Onofrio was cast to play the part of Bozo in the first Toxic Avenger film; however, before filming began, D'Onofrio brashly asked for a pay raise and was immediately fired. D'Onofrio was replaced by actor Gary Schneider.
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