Continuity mistake: When Paris is talking to the innkeeper about the orange grove she is buying in Florida, the strap of her purse keeps changing places. Sometimes it is lying over her coat and other times her coat is more open and it is lying across her tee shirt. It goes back and forth throughout the scene. (01:00:35)
Continuity mistake: When Ed the hotel manager and Rhodes discover the actress' body, they go rushing to room 10. When Rhodes enters the bathroom where he left the convict, Ed is standing behind him with his right arm by his side, yet in the following shot from the window, he now has his right hand on the bathroom doorframe. (00:31:25)
Revealing mistake: When John Cusack is coming out of the motel grounds looking for Jake Busey, the gate is banging away furiously from the wind but the rain is coming straight down. The rain should be sideways if the gate is banging so much from the wind.
Audio problem: When Ed picks up the hooker and they are driving and talking it is a pretty quiet conversation considering that Ed busted out one of the windows to get Rebecca DeMourney's cell phone away from her. There should be some noise from the wind in the broken window. (00:09:50 - 00:12:30)
Continuity mistake: When Ed is shot he falls to the ground and his jacket is open exposing the 2 gun shot wounds but when Paris runs over to him his jacket is closed and she has to open it to see his wounds. (01:20:20)
Factual error: The Spanish phrase, "¿Cuál es la punta de vivir?" keeps getting repeated throughout the movie, translated as "what is the point of living?" It's supposedly uttered by a Spanish-speaking person. Guess that person spoke Google Translate; the word "punta" means "point," all right, but it means a geographic point (like "Oyster Point"). The actual phrase in Spanish would be, "¿Cuál es la razón para la vida?"
Character mistake: There's no way that using a regular needle and thread to sew up that wound would work the way it's shown. Anybody who knew what they were doing - which John Cusack is portrayed as knowing - would also know that using unsterilized materials and instruments without a sterile field from an uncleaned massive open wound is a great way to kill your patient.
Suggested correction: The main plot of this film takes place inside the head of a murderer with dissociative identity disorder. The fact that stitching up a wound in that matter wouldn't work is irrelevant to the fact that it is how Malcolm is playing out the scenario in his head.
You're making a good point to invalidate a "character mistake", but couldn't the entry be reclassified as a "factual mistake" and stand as written?
Continuity mistake: When Ginny is about to open the bathroom door, the position of the bolt changes between shots. (00:40:35)
Continuity mistake: When the man bursts into the motel, Larry is watching Wheel of Fortune. The words on the screen change between when we see the screen and when the man bursts in. However it's the same game on the TV. (00:04:20)
Revealing mistake: When the woman Ed hit dies, her eyes move. (01:00:30)
Continuity mistake: Right before Ginny leaves the bathroom to find her husband dead, the knob on the lock is down. In the closeup, the knob is horizontal. (00:40:55)
Continuity mistake: When Ed is talking to the husband of the woman he just hit with his limo, as he looks to his left to see a boy, his right hand is not on the husband's shoulder, yet in the next shot it is. (00:09:00)
Continuity mistake: When Paris waves down Ed in his car she is seen about 5 feet in front of her car but when the scene changes to Ed's perspective she is now seen standing even with the hood of her car. (00:12:00)
