Trivia: Co-star Suzanne Shepherd first read the script, and was absolutely horrified by the explicit sexual content. She broke down crying and begged to not do the film. However, she changed her mind when she met director John Waters, who managed to convince her to stay on.
Trivia: Natalie Portman considers this movie to be her first one that helped her get away from her "Star Wars image".
Trivia: In the original script the movie was supposed to be set in New York City, but after the September 11 attacks the location was moved to Baltimore.